New

Research Scientist I

Broad Institute
paid time off, paid holidays, 401(k), retirement plan
United States, Massachusetts, Cambridge
Dec 11, 2025
Description & Requirements Reducing the burden of serious mental illness through research, the Stanley Center aims to exploit the most advanced technologies for human genetic analysis in order to understand disease mechanisms for psychiatric disorders, identify potential biomarkers, and ignite needed progress in therapeutics. Our goal is to derive biological insights from disease associated genes, contribute to new understandings of pathogenesis, the identification of biomarkers, and above all, new treatments. The Broad Institute is in search of a highly motivated and capable Research Scientist to join the Pan Lab at the Stanley Center for Psychiatric Research. The candidate will develop gene-specific cellular, molecular assays, working with a multidisciplinary team to validate disease associated phenotypes in cellular models including cell lines and iPSC- induced models. Excellent technical optimization and problem-solving skills will be required. OVERALL RESPONSIBILITY The successful candidate will develop, establish, and routinely perform cellular protocols to probe the molecular and cellular mechanism of how genetic variants impact protein and cellular function and confer disease risk. Support in vitro biophysical and/or cellular assays to understand protein function in both normal and dysfunctional brains. The researcher will be responsible for communicating results to the scientific community through conference presentations and publications, and within Broad Institute internal communications. Minimum requirements Expertise in high throughput assay development. Strong trouble shooting skills. Experience in ion channel assay development is strongly preferred. Ph.D. in Neuroscience or related life science field or MS with 20 years of a proven track record of experience will also be considered. Outstanding personal initiative and communication skills.Collaborative and enjoy team working environment. The successful candidate will be a results-focused, team-oriented, creative bench scientist able to excel in a fast-paced environment. She or he must be self-motivated, detail-oriented, and exhibit strong problem-solving skills. In addition, the successful candidate should be a clear and effective communicator, demonstrating strong interpersonal skills to enable collaboration with project teams, peers, and management in identifying and achieving research goals. The expected base pay range for this position as listed above is based on a 40 hour per week schedule. Broad provides pay ranges representing its reasonable and good faith estimate of what the organization reasonably expects to pay for a position at the time of posting. Actual compensation will vary based on factors including but not limited to, relevant skills, experience, education, qualifications, and other factors permissible by law. At Broad, your base pay is just one part of a comprehensive total rewards package. From day one, this role offers a competitive benefits package including medical, dental, vision, life, and disability insurance; a 401(k) retirement plan; flexible spending and health savings accounts; at least 13 paid holidays; winter closure; paid time off; parental and family care leave; and an employee assistance program, among other Broad benefits. The Broad Institute is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, disability, protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations. Should you need a reasonable accommodation to complete the application or interview process, please contact recruiting@broadinstitute.org for assistance.